Three clinically-dosed formulas for the mitochondria. NAD⁺, NMN, and NR. Sold individually. Built for the long climb.
ZYVA is a new standard for cellular supplementation. Three formulas, one protocol, designed for people who take the long view of their own biology. Every dose is clinically calibrated and third-party verified. No filler. No noise.
Every active backed by peer-reviewed human research. No proprietary blends, no guesswork.
Clinical-grade doses that match the studies. Not arbitrary amounts for label claims.
Single actives where the research says enough. Synergistic stacks only when the pathway demands more.
For people who think in decades, not weeks. Optimized for healthspan, not headlines.
Nicotinamide riboside, stacked with resveratrol and quercetin. Advanced cellular defense that sets the NAD⁺ baseline for everything ahead of you, from the early meeting to the late training session.
1,200 mg of pharmaceutical-grade NAD⁺ per serving. Dosed at the level used in peer-reviewed clinical trials, not a token amount. The anchor of the ZYVA protocol.
500 mg of β-nicotinamide mononucleotide in a phospholipid carrier. Enhanced absorption, formulated for the overnight repair cycle, the hours where the body does its quietest, most important work.
We start with NAD⁺, the coenzyme every cell needs for energy production. Levels decline ~50% by age 60.
NMN and NR are the two best-studied NAD⁺ precursors. We offer both, separately, so you choose.
Liposomal encapsulation can improve absorption several fold over standard capsule delivery for sensitive molecules.
Clinical doses. 1,200 mg NAD⁺ per serving, the level used in published trials, not a token amount.
Ingredients supported by human clinical research, not just in vitro or animal data.
We can explain how and why each compound works at the molecular level.
Premium-grade raw materials with full traceability from source to bottle.
Every batch tested for potency, purity, and contaminants. Certificates of Analysis available per lot.
Formulas refined through long-term use, performance feedback, and ongoing review of the literature.
NAD⁺ is the engine molecule of cellular metabolism. It regulates over 500 enzymatic reactions and is required for mitochondrial energy production, DNA repair, and circadian rhythm. By age 60, cellular NAD⁺ levels fall by roughly half.
Cellular defense. Resveratrol and quercetin stacked with NR. Two capsules with your first water of the day.
The anchor. A full clinical dose of NAD⁺ for cellular energy. Two capsules, any time of day, with or without food.
Phospholipid-encapsulated for enhanced absorption. Just one capsule, whenever works. The liposomal delivery does the rest.
ZYVA was built for people who refuse to settle. Optimizing your biology isn't about living forever. It's about living better, today, and not losing a step ten years from now.
Performance, resilience, clarity, longevity. These aren't buzzwords. They're the outcomes of giving your body what it needs, when it needs it, at doses that actually move the needle.
Peak output, daily
Bounce back stronger
Sharper between meals
Healthspan extended

NAD+ powers every cell in your body. Why levels drop with age, what the research actually says, and how precursors like NMN and NR fit in.

Two molecules, two absorption pathways, two clinical profiles. A clear breakdown of which fits which goal, and when the research actually matters.

Most NMN never reaches your bloodstream intact. Liposomal encapsulation changes that, and the absorption data is striking.

Levels drop roughly 50% by middle age. The mechanisms, CD38, PARP, sirtuin depletion, tell a clear story about why supplementation is worth the conversation.

NAD+ precursors fuel sirtuin enzymes. Resveratrol helps maintain their activity. Quercetin supports cellular cleanup. Why these three appear together in serious protocols.

Milligrams mean nothing without context. A practical guide to clinical doses, active forms, excipients, and the red flags that separate premium from marketing-first.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in your body. It powers cellular energy production, supports DNA repair, and helps maintain sirtuin proteins that regulate healthy aging. NAD+ levels naturally decline with age, research suggests levels can fall by up to 50% between your 20s and 50s. Supplementing with NAD+ precursors (NMN, NR) or direct NAD+ can help support normal cellular function as you age.
All three support NAD+ levels in your cells, but they work differently. NAD+ is the target molecule, direct supplementation delivers it straight. NMN and NR are precursors that your body converts into NAD+. NMN (nicotinamide mononucleotide) is one step closer to NAD+ in the biosynthesis pathway. NR (nicotinamide riboside) has the longest track record of published human clinical trials. ZYVA offers all three so you can choose based on your preference and goals.
Most users report noticing changes in energy within 1 to 2 weeks of consistent daily use. Mental clarity and sleep quality improvements are often reported within 2 to 4 weeks. Results vary by individual, factors like age, baseline NAD+ levels, overall health, and dose all play a role. We recommend taking ZYVA products consistently for 60 days before evaluating the full benefits.
We recommend taking ZYVA products in the morning with or without food. NAD+ supports cellular energy production, so morning dosing aligns with your natural energy cycle. Some people prefer taking with their first meal to reduce any chance of an upset stomach, though most people tolerate these well on an empty stomach.
Yes. ZYVA products are generally compatible with other supplements. NR Plus already combines NR with Resveratrol and Quercetin in one capsule. If you're taking magnesium, omega-3s, or a multivitamin, no interactions are anticipated. Always consult your healthcare provider if you're taking prescription medications or have a medical condition.
ZYVA products are well tolerated by most users. Some people report mild flushing or a slight warm sensation, this is far more common with niacin (a different form of B3) than with NMN or NR. Our formulas are free from unnecessary additives, fillers, and artificial ingredients that can cause digestive upset. If you experience any discomfort, try taking with food.
Yes to all of it. Every batch is third-party tested for purity, potency, and contaminants. Certificates of Analysis are published for each production lot. All ZYVA products are vegan, gluten-free, non-GMO, and free from major allergens. Our capsules are vegetarian cellulose, no gelatin, no artificial colors, flavors, or preservatives.
Most NMN studies showing meaningful NAD+ support used doses of 250 to 500mg daily. We chose 500mg because it represents the high end of the clinically studied range, giving you full-strength support without excess. Many competitors offer 250 to 300mg per serving. ZYVA gives you 500mg.
Standard NMN capsules face a real challenge getting through the stomach and into circulation intact. Liposomal encapsulation wraps the NMN in a lipid bilayer, the same kind of structure your own cell membranes use, which helps it survive digestion and reach your cells. The result is better uptake per milligram and one simple capsule a day.
No. Other NR-based supplements use nicotinamide riboside, a different NAD+ precursor. ZYVA NMN Liposomal 500mg uses NMN (nicotinamide mononucleotide), one step closer to NAD+ in the biosynthesis pathway. Same goal, different molecule.
Yes. NMN powder is water-soluble and can be dissolved in water or juice if you'd rather not swallow capsules. The taste is mildly bitter.
It's a fair question. Earlier research raised concerns about oral NAD+ bioavailability. More recent work, including studies published in 2020 to 2021, shows oral NAD+ supplementation can meaningfully raise blood NAD+ levels, especially at higher doses. NAD+ Pro 1200 uses 95% pharmaceutical-grade pure NAD+, the highest purity commercially available.
Dose matters. Research suggests a dose-response relationship, higher doses tend to support greater NAD+ levels. Most competitors offering direct NAD+ provide 250 to 500mg. NAD+ Pro 1200 at 1200mg is one of the highest doses available in capsule format, designed for people who want maximum support.
Not inherently better or worse, just different. NMN and NR are precursors your cells have to convert into NAD+. NAD+ Pro 1200 gives you the target molecule itself, no conversion step required. Some people prefer the directness, others prefer precursors for their longer clinical track record. We offer all three so you can choose.
Yes. These products can be stacked. Some people take NAD+ Pro 1200 daily and cycle in NMN or NR Plus periodically. As always, consult your healthcare provider, particularly if you're on medications.
They work together. NR supports healthy NAD+ levels. Resveratrol helps maintain SIRT1, a sirtuin protein that uses NAD+ to do its job. Quercetin is a senolytic flavonoid that supports cellular cleanup and complements the other two. One capsule format, three pathways, instead of buying three separate supplements.
NR Plus delivers 500mg NR per serving, up to double what many competitor products offer. Every dose is clearly stated on the label.
250mg trans-resveratrol per 2-capsule serving. Trans-resveratrol is the biologically active form used in research. Quercetin is delivered as Quercetin Phytosome (250mg), a phospholipid-complexed form for better absorption.
Yes. NR has been studied in humans at doses ranging from 100mg to 2,000mg per day with an excellent safety profile. Our 500mg dose is well within the clinically studied range. The most widely studied NR products use 300mg, NR Plus delivers more per serving with no evidence of increased risk at this dose.
New studies, founder letters, and early access to formulas. One email, last Sunday of the month. No filler, no affiliates.