Mountain summit at sunrise
FOUNDED IN AUSTIN, TX · TOPANGA, CA · BEND, OR

Engineered for
peak performance

NAD+ is the molecule your cells use for energy and repair. Three formulas, NMN, NAD+, and NR, dosed to the research and sold individually.

ZYVA product lineup
Peak performance Clinically dosed Third-party tested cGMP certified Liposomal delivery Zero fillers Gluten free Lab verified Manufactured in USA Peak performance Clinically dosed Third-party tested cGMP certified Liposomal delivery Zero fillers Gluten free Lab verified Manufactured in USA
OUR PROMISE

A protocol built for decades, not trends.

NAD+ is the molecule your cells use for energy and repair, and it declines as we age. Our three formulas are built to support you; precise doses, full-disclosure labels, third-party tested every batch.

Morning ritual at the window MORNING · 07:12 · AUSTIN
THE RANGE

Three formulas. One protocol.

ZYVA NAD+ Pro 1200 bottle with a stylized NAD+ molecular structure and faint mountains, on a warm dark editorial background

NAD+ Pro 1200.
The anchor molecule.

1,200 mg of NAD⁺ per serving. Dosed at the level used in published clinical trials, not a token amount. The anchor of the ZYVA protocol.

Cellular Energy
Metabolism Boost
Mental Clarity
Common questions · NAD+ Pro 1200

Does oral NAD+ actually work? Doesn't it break down in digestion?

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It's a fair question. Earlier research raised concerns about oral NAD+ bioavailability. More recent work, including studies published in 2020 to 2021, shows oral NAD+ supplementation can meaningfully raise blood NAD+ levels, especially at higher doses. NAD+ Pro 1200 uses 95% pharmaceutical-grade pure NAD+, the highest purity commercially available.

Why 1200mg when others offer 500mg?

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Dose matters. Research suggests a dose-response relationship, higher doses tend to support greater NAD+ levels. Most competitors offering direct NAD+ provide 250 to 500mg. NAD+ Pro 1200 at 1200mg is one of the highest doses available in capsule format, designed for people who want maximum support.

Is direct NAD+ better than NMN or NR?

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Not inherently better or worse, just different. NMN and NR are precursors your cells have to convert into NAD+. NAD+ Pro 1200 gives you the target molecule itself, no conversion step required. Some people prefer the directness, others prefer precursors for their longer clinical track record. We offer all three so you can choose.

Can I stack NAD+ Pro with NMN or NR Plus?

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Yes. These products can be stacked. Some people take NAD+ Pro 1200 daily and cycle in NMN or NR Plus periodically. As always, consult your healthcare provider, particularly if you're on medications.

ZYVA NMN Liposomal bottle with a stylized NMN molecular structure and faint mountains, on a warm dark editorial background

NMN Liposomal.
While the body repairs.

500 mg of β-nicotinamide mononucleotide in a phospholipid carrier. Enhanced absorption, formulated for the overnight repair cycle, the hours where the body does its quietest, most important work.

NAD+ Production
Physical Stamina
Healthy Aging
Common questions · NMN Liposomal

Why 500mg? Isn't 250mg enough?

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Most NMN studies showing meaningful NAD+ support used doses of 250 to 500mg daily. We chose 500mg because it represents the high end of the clinically studied range, giving you full-strength support without excess. Many competitors offer 250 to 300mg per serving. ZYVA gives you 500mg.

Why liposomal? Does it actually matter?

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Standard NMN capsules face a real challenge getting through the stomach and into circulation intact. Liposomal encapsulation wraps the NMN in a lipid bilayer, the same kind of structure your own cell membranes use, which helps it survive digestion and reach your cells. The result is better uptake per milligram and one simple capsule a day.

Is this the same as other NR-based supplements?

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No. Other NR-based supplements use nicotinamide riboside, a different NAD+ precursor. ZYVA NMN Liposomal 500mg uses NMN (nicotinamide mononucleotide), one step closer to NAD+ in the biosynthesis pathway. Same goal, different molecule.

Can I open the capsule and mix it in water?

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Yes. NMN powder is water-soluble and can be dissolved in water or juice if you'd rather not swallow capsules. The taste is mildly bitter.

ZYVA NR Plus bottle with a stylized NR molecular structure and faint mountains, on a warm dark editorial background

NR Plus.
The full longevity stack.

Nicotinamide riboside, stacked with resveratrol and quercetin. Advanced cellular defense that sets the NAD⁺ baseline for everything ahead of you, from the early meeting to the late training session.

NR 500 mg · Resveratrol 250 mg · Quercetin 250 mg

DNA Repair
NAD+ Boost
Sirtuin Activation
Common questions · NR Plus

Why combine NR with Resveratrol and Quercetin?

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They work together. NR supports healthy NAD+ levels. Resveratrol helps maintain SIRT1, a sirtuin protein that uses NAD+ to do its job. Quercetin is a senolytic flavonoid that supports cellular cleanup and complements the other two. One capsule format, three pathways, instead of buying three separate supplements.

How does NR Plus compare to other NR supplements?

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NR Plus delivers 500mg NR per serving, up to double what many competitor products offer. Every dose is clearly stated on the label.

What form of resveratrol? What dose?

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250mg trans-resveratrol per 2-capsule serving. Trans-resveratrol is the biologically active form used in research. Quercetin is delivered as Quercetin Phytosome (250mg), a phospholipid-complexed form for better absorption.

Is 500mg NR safe?

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Yes. NR has been studied in humans at doses ranging from 100mg to 2,000mg per day with an excellent safety profile. Our 500mg dose is well within the clinically studied range. The most widely studied NR products use 300mg, NR Plus delivers more per serving with no evidence of increased risk at this dose.

The ZYVA Approach

Science for optimized living.

Better supplementation isn't about more. It's the right dose, and nothing to hide on the label. Four principles guide every formula we make.
§ 01

Clinical doses

The amounts used in human studies, not trimmed to hit a price. 1,200 mg NAD⁺, 500 mg NMN, 500 mg NR.

§ 02

Nothing hidden

Every active and every milligram is on the label. No proprietary blends, nothing we can't explain.

§ 03

Targeted formulas

A single active when the research supports one. A stack only when the ingredients work better together, like resveratrol and quercetin alongside NR.

§ 04

Tested every batch

Third-party tested for potency, purity, and contaminants, with a Certificate of Analysis on every lot.

Age on your terms - ZYVA Scientific
MOLECULE

Three molecules, one pathway.

NAD⁺ · C₂₁H₂₇N₇O₁₄P₂
NICOTINAMIDE RIBOSE PHOSPHATE ADENINE PP
FIG · NAD⁺ · SIMPLIFIED

The destination.

The coenzyme your cells actually run on, powering energy, DNA repair, and the proteins tied to healthy aging. Levels fall by about half by 60; NAD⁺ Pro delivers it directly.

Cellular energy+

Mitochondria use NAD⁺ to turn food into ATP, the fuel every cell spends.

DNA repair+

Repair enzymes spend NAD⁺ fixing everyday DNA damage; keeping it topped up helps that upkeep keep pace.

Sirtuins & aging+

Sirtuins, the proteins linked to healthy aging, can't work without NAD⁺.

TogetherNMN and NR feed the pathway; NAD⁺ Pro delivers the molecule itself. Take one, or stack them, the destination's the same.
THE STACK

Take all three. Or just one.

Each formula stands alone · built to stack
ZYVA NMN Liposomal, NR Plus, and NAD+ Pro 1200 in a row, mountain mark glowing gold behind them on a dark editorial backdrop THE TRIO · ONE PROTOCOL
01 · NR

NR Plus

Cellular defense. Resveratrol and quercetin stacked with NR. Two capsules with your first water of the day.

2 CAPS
02 · NAD⁺

NAD+ Pro 1200

The anchor. A full clinical dose of NAD⁺ for cellular energy. Two capsules, any time of day, with or without food.

2 CAPS
03 · NMN

NMN Liposomal, one a day

Phospholipid-encapsulated for enhanced absorption. Just one capsule, whenever works. The liposomal delivery does the rest.

1 CAP
Live longer. Live brighter. - ZYVA Scientific
JOURNAL

Science, decoded.

6 essays · research-backed
What is NAD+? A Cellular Energy Primer
Foundations8 MIN READ

What is NAD+? A cellular energy primer.

NAD+ powers every cell in your body. Why levels drop with age, what the research actually says, and how precursors like NMN and NR fit in.

READ ESSAY →
NMN vs NR: Choosing Your NAD+ Precursor
Research10 MIN READ

NMN vs NR: choosing your precursor.

Two molecules, two absorption pathways, two clinical profiles. A clear breakdown of which fits which goal, and when the research actually matters.

READ ARTICLE →
Why Liposomal Delivery Matters
Bioavailability7 MIN READ

Why liposomal delivery matters.

Most NMN never reaches your bloodstream intact. Liposomal encapsulation changes that, and the absorption data is striking.

READ ARTICLE →
The NAD+ Decline Curve
Science9 MIN READ

The NAD+ decline curve: what changes after 40.

Levels drop roughly 50% by middle age. The mechanisms, CD38, PARP, sirtuin depletion, tell a clear story about why supplementation is worth the conversation.

READ ARTICLE →
The Longevity Triangle
Stacking11 MIN READ

The longevity triangle: NAD+, resveratrol, quercetin.

NAD+ precursors fuel sirtuin enzymes. Resveratrol helps maintain their activity. Quercetin supports cellular cleanup. Why these three appear together in serious protocols.

READ ARTICLE →
Reading a Supplement Label
Transparency6 MIN READ

Reading a supplement label: what to actually look for.

Milligrams mean nothing without context. A practical guide to clinical doses, active forms, excipients, and the red flags that separate premium from marketing-first.

READ ARTICLE →
VOICES WE FOLLOW

The work that shaped us.

Long-form science, not headlines
The Drive podcast cover art
The Drive
Peter Attia, MD
Huberman Lab podcast cover art
Huberman Lab
Andrew Huberman, PhD
FoundMyFitness podcast cover art
FoundMyFitness
Rhonda Patrick, PhD
Independent recommendations. No affiliation, no sponsorship.
ANSWERED

Real questions. Straight answers.

Common to all three formulas
The Basics

What is NAD+ and why do I need it?

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NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in your body. It powers cellular energy production, supports DNA repair, and helps maintain sirtuin proteins that regulate healthy aging. NAD+ levels naturally decline with age, research suggests levels can fall by up to 50% between your 20s and 50s. Supplementing with NAD+ precursors (NMN, NR) or direct NAD+ can help support normal cellular function as you age.

What's the difference between NMN, NR, and NAD+?

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All three support NAD+ levels in your cells, but they work differently. NAD+ is the target molecule, direct supplementation delivers it straight. NMN and NR are precursors that your body converts into NAD+. NMN (nicotinamide mononucleotide) is one step closer to NAD+ in the biosynthesis pathway. NR (nicotinamide riboside) has the longest track record of published human clinical trials. ZYVA offers all three so you can choose based on your preference and goals.

How long before I notice results?

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Most users report noticing changes in energy within 1 to 2 weeks of consistent daily use. Mental clarity and sleep quality improvements are often reported within 2 to 4 weeks. Results vary by individual, factors like age, baseline NAD+ levels, overall health, and dose all play a role. We recommend taking ZYVA products consistently for 60 days before evaluating the full benefits.

When should I take this, morning or night?

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We recommend taking ZYVA products in the morning with or without food. NAD+ supports cellular energy production, so morning dosing aligns with your natural energy cycle. Some people prefer taking with their first meal to reduce any chance of an upset stomach, though most people tolerate these well on an empty stomach.

Can I take these with other supplements?

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Yes. ZYVA products are generally compatible with other supplements. NR Plus already combines NR with Resveratrol and Quercetin in one capsule. If you're taking magnesium, omega-3s, or a multivitamin, no interactions are anticipated. Always consult your healthcare provider if you're taking prescription medications or have a medical condition.

Are there any side effects?

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ZYVA products are well tolerated by most users. Some people report mild flushing or a slight warm sensation, this is far more common with niacin (a different form of B3) than with NMN or NR. Our formulas are free from unnecessary additives, fillers, and artificial ingredients that can cause digestive upset. If you experience any discomfort, try taking with food.

Third-party tested? Vegan? Gluten-free?

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Yes to all of it. Every batch is third-party tested for purity, potency, and contaminants. Certificates of Analysis are published for each production lot. All ZYVA products are vegan, gluten-free, non-GMO, and free from major allergens. Our capsules are vegetarian cellulose, no gelatin, no artificial colors, flavors, or preservatives.

Woman climber above the cloud line on a snowy summit at dawn
Dispatch · monthly

Field notes from the edge of longevity research.

New studies, founder letters, and early access to formulas. One email, last Sunday of the month. No filler, no affiliates.

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